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SERAC1 polyclonal antibody

货号: BS31457

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31457

Product Name :SERAC1 polyclonal antibody

Swiss-Prot :Q96JX3

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Protein SERAC1: Facilitates the transport of serine from the cytosol to the mitochondria by interacting with and stabilizing Sideroflexin-1 (SFXN1), a mitochondrial serine transporter, playing a fundamental role in the one-carbon cycle responsible for the synthesis of nucleotides needed for mitochondrial DNA replication . Plays an important role in the phosphatidylglycerol (PG) remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking . Specifically involved in the exchange of the sn-1 acyl chain from PG 16:0/18:1(9Z) (also known as 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)) to PG 18:0/18:1(9Z) (also known as 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)), a step needed in the bis(monoacylglycerol)phosphate biosynthetic pathway . May have acyltransferase activity although the mechanism for PG remode...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SERAC1 protein.

BiowMW :~74.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein SERAC1; Serine active site-containing protein 1

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human SERAC1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD55 expression in Raji (A), K562 (B) whole cell lysates.

免疫沉淀（IP）