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TMEM66 polyclonal antibody

货号: BS31449

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS31449

Product Name :TMEM66 polyclonal antibody

Swiss-Prot :Q96BY9

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Store-operated calcium entry-associated regulatory factor: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TMEM66 protein.

BiowMW :~37.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SARAF; XTP3; Store-operated calcium entry-associated regulatory factor; SARAF; SOCE-associated regulatory factor; HBV X-transactivated gene 3 protein; HBV XAg-transactivated protein 3; Protein FOAP-7; Transmembrane protein 66

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TMEM66.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD115 (Phospho-Y561) expression in HuT78 (A), Jurkat (B), mouse embryo (C), rat brain (D) whole cell lysates.