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DTD2 polyclonal antibody

货号: BS31428

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31428

Product Name :DTD2 polyclonal antibody

Swiss-Prot :Q96FN9

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :D-aminoacyl-tRNA deacylase 2: Deacylates mischarged D-aminoacyl-tRNAs (By similarity). Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS (By similarity). Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids (By similarity). Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr), has no activity on correctly charged L-tyrosyl-tRNA(Tyr) (By similarity). By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality. In contrast to DTD1, deacylates L-Ala mischarged on tRNA(Thr)(G4.U69) by alanine-tRNA ligase AARS . Can deacylate L-Ala due to a relaxed specificity for substrate chirality caused by the trans conformation of the Gly-Pro motif in the active site . Also...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of DTD2 protein.

BiowMW :~18.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C14orf126; Probable D-tyrosyl-tRNA(Tyr) deacylase 2; D-tyrosyl-tRNA deacylase 2

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human DTD2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HSP90 alpha expression in Hela (A), NIH3T3 (B), mouse brain (C), rat brain (D) whole cell lysates.

免疫沉淀（IP）