Product Name :TLDC1 polyclonal antibody
Applications :WB, IHC, FC
Application_all :WB (1/1000 - 1/2000), IHC (1/50 - 1/200), FC (1/10 - 1/50)
Background :MTOR-associated protein MEAK7: Activates an alternative mTOR signaling pathway through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration . Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome . Binds to the vacuolar-type ATPase (V-ATPase) complex, triggering a conformational change and is likely to regulate its activity . No effect on V-ATPase activity was observed in vitro in one study although it was suggested that it may have inhibitory activity in vivo . However, another study showed that it can promote V-ATPase activity . Protects neuronal cells against oxidative stress (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TLDC1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA1609; TLD domain-containing protein 1; TBC/LysM-associated domain-containing protein 1
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human TLDC1.
Modification :Unmodification
