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ATP6V0B polyclonal antibody

货号: BS31414

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31414

Product Name :ATP6V0B polyclonal antibody

Swiss-Prot :Q99437

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :V-type proton ATPase 21 kDa proteolipid subunit c'': Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular environment (By similarity). The V-ATPase complex also acts as an activator for mTORC1 on lysosomal membrane by promoting the guanine nucleotide exchange factor (GEF) of the Ragulator complex, thereby enabling mTORC1 recruitment

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ATP6V0B protein.

BiowMW :~21.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATP6F; V-type proton ATPase 21 kDa proteolipid subunit; V-ATPase 21 kDa proteolipid subunit; Vacuolar proton pump 21 kDa proteolipid subunit; hATPL

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human ATP6V0B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ACAA1 expression in A549 (A), Jurkat (B), mouse kidney (C), rat liver (D) whole cell lysates.