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PEMT polyclonal antibody

货号: BS31399

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31399

Product Name :PEMT polyclonal antibody

Swiss-Prot :Q9UBM1

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Phosphatidylethanolamine N-methyltransferase: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure . Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step . Responsible for approximately 30% of hepatic PC with the CDP-choline pathway accounting for the other 70% (Probable)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PEMT protein.

BiowMW :~22.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PEMPT; PNMT; Phosphatidylethanolamine N-methyltransferase; PEAMT; PEMT; PEMT2

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human PEMT.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MTHFD2 expression in Hela (A), 293 (B), MOLT4 (C), mouse heart (D) whole cell lysates.

免疫沉淀（IP）