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TFB2M polyclonal antibody

货号: BS31392

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31392

Product Name :TFB2M polyclonal antibody

Swiss-Prot :Q9H5Q4

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Dimethyladenosine transferase 2, mitochondrial: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA . In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand . Stimulates transcription independently of the methyltransferase activity

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TFB2M protein.

BiowMW :~45.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NS5ATP5; Dimethyladenosine transferase 2, mitochondrial; Hepatitis C virus NS5A-transactivated protein 5; HCV NS5A-transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; h-mtTFB; h-mtTFB2; hTFB2M; mtTFB2; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human TFB2M.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PRKAR1A expression in U87MG (A) whole cell lysates.