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RFT1 polyclonal antibody

货号: BS31389

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31389

Product Name :RFT1 polyclonal antibody

Swiss-Prot :Q96AA3

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1: Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues . However, the intramembrane lipid transporter activity could not be...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of RFT1 protein.

BiowMW :~60.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein RFT1 homolog

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human RFT1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Glutathione Peroxidase expression in rat liver (A) whole cell lysates.

免疫沉淀（IP）