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YME1L1 polyclonal antibody

货号: BS31368

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31368

Product Name :YME1L1 polyclonal antibody

Swiss-Prot :Q96TA2

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :ATP-dependent zinc metalloprotease YME1L1: ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region . Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism . Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins . Required to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1) . Involved in the mitochondrial adaptation in response to various signals, such as stress or developmental cues, by mediating degradation of mitochondrial proteins t...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of YME1L1 protein

BiowMW :~86.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FTSH1; YME1L; ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease FtsH1; Meg-4; Presenilin-associated metalloprotease; PAMP; YME1-like protein 1

Immunogen :Recombinant fusion protein of human YME1L1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Gamma-enolase expression in Hela (A), Jurkat (B), 293T (C) whole cell lysates.