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ST3GAL2 polyclonal antibody

货号: BS31336

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31336

Product Name :ST3GAL2 polyclonal antibody

Swiss-Prot :Q16842

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2: A beta-galactoside alpha2-3 sialyltransferase primarily involved in terminal sialylation of ganglio and globo series glycolipids . Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the nucleotide sugar donor CMP-Neu5Ac onto acceptor Galbeta-(1->3)-GalNAc-terminated glycoconjugates through an alpha2-3 linkage . Sialylates GM1/GM1a, GA1/asialo-GM1 and GD1b gangliosides to form GD1a, GM1b and GT1b, respectively . Together with ST3GAL3, primarily responsible for biosynthesis of brain GD1a and GT1b that function as ligands for myelin-associated glycoprotein MAG on axons, regulating MAG expression and axonal myelin stability and regeneration (By similarity). Via GT1b regulates TLR2 signaling in spinal cord microglia in response to nerve injury (By similarity). Responsible for the sialylation of the pluripotent stem cell- and cancer stem cell-associated antigen SS...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ST3GAL2 protein

BiowMW :~40.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SIAT4B; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 3-sialyltransferase 2; Alpha 2 3-ST 2; Beta-galactoside alpha-2 3-sialyltransferase 2; Gal-NAc6S; Gal-beta-1 3-GalNAc-alpha-2 3-sialyltransferase; ST3Gal II; ST3GalII; ST3GalA.2; Sialyltransferase 4B; SIAT4-B

Immunogen :Recombinant fusion protein of human ST3GAL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of RNase H1 expression in mouse testis (A), rat thymus (B) whole cell lysates.