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SAR1A polyclonal antibody

货号: BS31315

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31315

Product Name :SAR1A polyclonal antibody

Swiss-Prot :Q9NR31

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Background :Small COPII coat GTPase SAR1A: Small GTPase that cycles between an active GTP-bound and an inactive GDP-bound state and mainly functions in vesicle-mediated endoplasmic reticulum (ER) to Golgi transport. The active GTP-bound form inserts into the endoplasmic reticulum membrane where it recruits the remainder of the coat protein complex II/COPII. The coat protein complex II assembling and polymerizing on endoplasmic reticulum membrane is responsible for both the sorting of cargos and the deformation and budding of membranes into vesicles destined to the Golgi . The GTPase activity of SAR1 by controlling the timing of COPII budding regulates the size of the formed vesicles and is important for cargo selection depending on their size . Together with SEC16A, forms the organized scaffold defining endoplasmic reticulum exit sites (ERES), some specific domains of the endoplasmic reticulum where COPII vesicles form . In ad...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SAR1A protein

BiowMW :~22.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SAR1; SARA; SARA1; GTP-binding protein SAR1a; COPII-associated small GTPase

Immunogen :Recombinant fusion protein of human SAR1A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD79a expression in Raji (A) whole cell lysates.

Immunohistochemical analysis of CD79a staining in rat spleen formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.