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RNF212 polyclonal antibody

货号: BS31310

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31310

Product Name :RNF212 polyclonal antibody

Swiss-Prot :Q495C1

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Probable E3 SUMO-protein ligase RNF212: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of RNF212 protein

BiowMW :~33.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Probable E3 SUMO-protein ligase RNF212; RING finger protein 212

Immunogen :Recombinant fusion protein of human RNF212.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of NDUFS6 expression in mouse heart (A), rat brain (B) whole cell lysates.

免疫沉淀（IP）