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MSL-1 polyclonal antibody

货号: BS31268

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31268

Product Name :MSL-1 polyclonal antibody

Swiss-Prot :Q68DK7

Host :Rabbit

Reactivity :Human, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Male-specific lethal 1 homolog: Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction . The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac . The MSL complex is also involved in gene dosage by promoting up-regulation of genes expressed by the X chromosome (By similarity). X up-regulation is required to compensate for autosomal biallelic expression (By similarity). The MSL complex also participates in gene dosage compensation by promoting expression of Tsix non-coding RNA (By similarity). Within the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation . Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of hist...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MSL-1 protein

BiowMW :~67.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MSL1L1; Male-specific lethal 1 homolog; MSL-1; Male-specific lethal 1-like 1; MSL1-like 1; Male-specific lethal-1 homolog 1

Immunogen :Recombinant fusion protein of human MSL-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of DUSP14 expression in HeLa (A), mouse testis (B), rat testis (C) whole cell lysates.

免疫沉淀（IP）