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FNBP1 polyclonal antibody

货号: BS31211

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31211

Product Name :FNBP1 polyclonal antibody

Swiss-Prot :Q96RU3

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Formin-binding protein 1: May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of FNBP1 protein

BiowMW :~71.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FBP17; KIAA0554; Formin-binding protein 1; Formin-binding protein 17; hFBP17

Immunogen :Recombinant fusion protein of human FNBP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Laminin Receptor expression in PC3 (A), THP1 (B), Hela (C), mouse liver (D), mouse brain (E), rat liver (F), rat brain whole cell lysates.