Product Name :FLVCR2 polyclonal antibody
Application_all :WB (1/500 - 1/2000)
Background :Choline/ethanolamine transporter FLVCR2: Choline uniporter that specifically mediates choline uptake at the blood-brain-barrier . Responsible for the majority of choline uptake across the blood-brain-barrier from the circulation into the brain (By similarity). Choline, a nutrient critical for brain development, is a precursor of phosphatidylcholine, as well as betaine (By similarity). Also mediates transport of ethanolamine . Choline and ethanolamine transport is not coupled with proton transport and is exclusively driven by the choline gradient across the plasma membrane . However, the presence of an inwardly directed proton gradient enhances choline uptake (By similarity). Also acts as a heme b transporter . Required to regulate mitochondrial respiration processes, ATP synthesis and thermogenesis . At low heme levels, interacts with components of electron transfer chain (ETC) complexes and ATP2A2, leading to ubiquitin-medi...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FLVCR2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C14orf58; Feline leukemia virus subgroup C receptor-related protein 2; Calcium-cHeLate transporter; CCT
Immunogen :Recombinant fusion protein of human FLVCR2.
Modification :Unmodification
