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ATP11C polyclonal antibody

货号: BS31160

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31160

Product Name :ATP11C polyclonal antibody

Swiss-Prot :Q8NB49

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Phospholipid-transporting ATPase IG: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane . Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages . Required for B cell differentiation past the pro-B cell stage (By similarity). Seems to mediate PS flipping in pro-B cells (By similarity). May be involved in the transport of cholestatic bile acids (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ATP11C protein

BiowMW :~129 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATPIG; ATPIQ; Probable phospholipid-transporting ATPase IG; ATPase IQ; ATPase class VI type 11C

Immunogen :Recombinant fusion protein of human ATP11C.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TRK A/B (Phospho-Y490/516) expression in C6 treated with Pervanadate (A) whole cell lysates.

免疫沉淀（IP）