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ACD polyclonal antibody

货号: BS31151

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS31151

Product Name :ACD polyclonal antibody

Swiss-Prot :Q96AP0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Adrenocortical dysplasia protein homolog: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ACD protein

BiowMW :~49.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PIP1; PTOP; TINT1; TPP1; Adrenocortical dysplasia protein homolog; POT1 and TIN2-interacting protein

Immunogen :Recombinant fusion protein of human ACD.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PDI expression in A549 (A), THP1 (B), mouse liver (C), rat liver (D) whole cell lysates.

免疫沉淀（IP）