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A4GALT polyclonal antibody

货号: BS31150

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31150

Product Name :A4GALT polyclonal antibody

Swiss-Prot :Q9NPC4

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Lactosylceramide 4-alpha-galactosyltransferase: Glycosyltransferase involved in biosynthesis of P1, P(k) and the rare NOR antigens of P1PK histo-blood group system . Catalyzes the transfer of galactose from UDP-alpha-D-galactose in an alpha1,4 linkage to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)), also known as P(k) antigen or CD77 . Globoside Gb3Cer/P(k)/CD77 is a root structure in biosynthesis pathway of neutral glycosphingolipids of the globo-series. Broadly expressed in cell membranes of immune cells and other tissues, Gb3Cer/P(k)/CD77 antigen may participate in mechanisms that regulate cell-cell interactions and cell differentiation. In germinal center B cells, Gb3Cer/CD77 interacts with CD19 to drive centroblast-to-centrocyte transition, B cell receptor complex assembly and T follicular helper cell differentiation. In epit...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of A4GALT protein

BiowMW :~40.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :A14GALT; A4GALT1; Lactosylceramide 4-alpha-galactosyltransferase; Alpha-1 4-N-acetylglucosaminyltransferase; Alpha-1 4-galactosyltransferase; Alpha4Gal-T1; CD77 synthase; Globotriaosylceramide synthase; Gb3 synthase; P1/Pk synthase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Immunogen :Recombinant fusion protein of human A4GALT.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Dystrophin expression in rat heart (A) whole cell lysates.