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IL-25 polyclonal antibody

货号: BS31149

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31149

Product Name :IL-25 polyclonal antibody

Swiss-Prot :Q9H293

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/200), IF/ICC (1/100 - 1/500)

Background :Interleukin-25: Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production . Promotes and augments T-helper type 2 responses locally or systemically . Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction (By similarity). In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13 . Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways . Inhibits the differentiation of T-helper (Th17) cells via the production of IL4, IL5 and IL13

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of IL-25 protein.

BiowMW :~20.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IL17E; Interleukin-25; IL-25; Interleukin-17E; IL-17E

Immunogen :Recombinant protein of human IL-25.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of BCL2 expression in mouse spleen (A) whole cell lysates.

免疫沉淀（IP）