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IWS1 polyclonal antibody

货号: BS31145

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31145

Product Name :IWS1 polyclonal antibody

Swiss-Prot :Q96ST2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB (1/500 - 1/2000), IF/ICC (1/50 - 1/200)

Background :Protein IWS1 homolog: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of IWS1 protein.

BiowMW :~92.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IWS1L; Protein IWS1 homolog; IWS1-like protein

Immunogen :Recombinant fusion protein of human IWS1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of FGF2 expression in K562 (A) whole cell lysates.

免疫沉淀（IP）