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MAP1 polyclonal antibody

货号: BS31140

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31140

Product Name :MAP1 polyclonal antibody

Swiss-Prot :Q96BY2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Modulator of apoptosis 1: Retrotransposon-derived protein that forms virion-like capsids (By similarity). Acts as an effector of BAX during apoptosis: enriched at outer mitochondria membrane and associates with BAX upon induction of apoptosis, facilitating BAX-dependent mitochondrial outer membrane permeabilization and apoptosis . Required for death receptor-dependent apoptosis . When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation . Also promotes autophagy: promotes phagophore closure via association with ATG8 proteins . Acts as an inhibitor of the NFE2L2/NRF2 pathway via interaction with SQSTM1: interaction promotes dissociation of SQSTM1 inclusion bodies that sequester KEAP1, relieving inactivation of the BCR(KEAP1) complex

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MAP1 protein.

BiowMW :~39.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PNMA4; Modulator of apoptosis 1; MAP-1; MAP1; Paraneoplastic antigen Ma4

Immunogen :Recombinant fusion protein of human MAP1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD115 expression in A549 (A) whole cell lysates.

免疫沉淀（IP）