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HRP2 polyclonal antibody

货号: BS31134

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31134

Product Name :HRP2 polyclonal antibody

Swiss-Prot :Q7Z4V5

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/200)

Background :Hepatoma-derived growth factor-related protein 2: Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C) . Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters . Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs . Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2 . Involved in cellular growth control, through the regulation of cyclin D1 expression

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HRP2 protein.

BiowMW :~74.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HDGF2; Hepatoma-derived growth factor-related protein 2; HRP-2; Hepatoma-derived growth factor 2; HDGF-2

Immunogen :Recombinant fusion protein of human HRP2

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Serpin A3 expression in HEK293T (A), Hela (B) whole cell lysates.

Immunohistochemical analysis of Serpin A3 staining in human pancreas cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.