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Kv10.2 polyclonal antibody

货号: BS31108

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31108

Product Name :Kv10.2 polyclonal antibody

Swiss-Prot :Q8NCM2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/1000 - 1/2000), IHC (1/100 - 1/200)

Background :Voltage-gated delayed rectifier potassium channel KCNH5: Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not inactivate . The kinetic is characterized by a slow activation time course and a small voltage dependence of the activation time constants, therefore, starts to open at more negative voltages . The activation kinetics depend on the prepulse potential and external divalent cation concentration . The time course of activation is biphasic with a fast and a slowly activating current component . With negative prepulses, the current activation is delayed and slowed down several fold, whereas more positive prepulses speed up activation, therefore the activation rate depends on holding potential

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Kv10.2 protein.

BiowMW :~112 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EAG2; Potassium voltage-gated channel subfamily H member 5; Ether-a-go-go potassium channel 2; hEAG2; Voltage-gated potassium channel subunit Kv10.2

Immunogen :A synthetic peptide encompassing a sequence of human Kv10.2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of p53 expression in CT26 (A), Beas2B (B), A375 (C) whole cell lysates.

Immunohistochemical analysis of p53 staining in human ovarian cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.