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KCNN2 polyclonal antibody

货号: BS31107

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31107

Product Name :KCNN2 polyclonal antibody

Swiss-Prot :Q9H2S1

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/1000 - 1/2000), IHC (1/100 - 1/200)

Background :Small conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin which binds the intracellular calcium allowing its opening . The current is characterized by a voltage-independent activation, an intracellular calcium concentration increase-dependent activation and a single-channel conductance of about 3 picosiemens . Also presents an inwardly rectifying current, thus reducing its already small outward conductance of potassium ions, which is particularly the case when the membrane potential displays positive values, above + 20 mV . The inward rectification could be due to a blockade of the outward current by intracellular divalent cations such as calcium and magnesium and could also be due to an intrinsic property of the channel pore, independent of...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KCNN2 protein.

BiowMW :~63.8 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Small conductance calcium-activated potassium channel protein 2; SK2; SKCa 2; SKCa2; KCa2.2

Immunogen :A synthetic peptide encompassing a sequence of human KCNN2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Thioredoxin 1 expression in mouse kidney (A), mouse testis (B), rat kidney (C) whole cell lysates.

免疫沉淀（IP）