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Histone H2A.X polyclonal antibody

货号: BS31104

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31104

Product Name :Histone H2A.X polyclonal antibody

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/1000 - 1/2000), IHC (1/200 - 1/500)

Background :Histone H2AX: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Histone H2A.X protein.

BiowMW :~15.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H2AX; Histone H2AX; H2a/x; Histone H2A.X

Immunogen :A synthetic peptide encompassing a sequence of mouse Histone H2A.X.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Galectin 3 expression in MCF7 (A), NIH3T3 (B) whole cell lysates.

免疫沉淀（IP）