产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

ASIC1 polyclonal antibody

货号: BS31094

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS31094

Product Name :ASIC1 polyclonal antibody

Swiss-Prot :P78348

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/1000 - 1/2000), IHC (1/50 - 1/200)

Background :Acid-sensing ion channel 1: Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory . Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inward currents . Displays high selectivity for sodium ions but can also permit the permeation of other cations . Regulates more or less directly intracellular calcium concentration and CaMKII phosphorylation, and thereby the density of dendritic spines. Modulates neuronal activity in the circuits underlying innate fear (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ASIC1 protein.

BiowMW :~59.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ACCN2; BNAC2; Acid-sensing ion channel 1; ASIC1; Amiloride-sensitive cation channel 2 neuronal; Brain sodium channel 2; BNaC2

Immunogen :A synthetic peptide encompassing a sequence of human ASIC1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ACTL8 expression in HepG2 (A), Raji (B), mouse liver (C), rat lung (D), rat kidney (E) whole cell lysates.

免疫沉淀（IP）