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MCOLN1 polyclonal antibody

货号: BS31055

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31055

Product Name :MCOLN1 polyclonal antibody

Swiss-Prot :Q9GZU1

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Mucolipin-1: Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis . Acts as a Ca(2+)-permeable cation channel with inwardly rectifying activity . Proposed to play a major role in Ca(2+) release from late endosome and lysosome vesicles to the cytoplasm, which is important for many lysosome-dependent cellular events, including the fusion and trafficking of these organelles, exocytosis and autophagy . Required for efficient uptake of large particles in macrophages in which Ca(2+) release from the lysosomes triggers lysosomal exocytosis. May also play a role in phagosome-lysosome fusion (By similarity). Involved in lactosylceramide trafficking indicative for a role in the regulation of late endocytic membrane fusion/fission events . By mediating lysosomal Ca(2+) release is involved in regulation of mTORC1 signaling and in mTOR/TF...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MCOLN1 protein

BiowMW :~65.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ML4; Mucolipin-1; MG-2; Mucolipidin

Immunogen :A synthetic peptide encompassing a sequence within the center region of human MCOLN1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CGRP2 expression in Hela (A), Jurkat (B) whole cell lysates.

免疫沉淀（IP）