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TMEM16J polyclonal antibody

货号: BS30994

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30994

Product Name :TMEM16J polyclonal antibody

Swiss-Prot :A1A5B4

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/2000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/100)

Background :Anoctamin-9: PKA-activated nonselective cation channel . Discriminates poorly among cations but is more permeable to Ca(2+) ions than to monovalent cations (By similarity). Acts as a calcium-activated calcium permeable channel which may operate as a endoplasmic reticulum (ER) Ca(2+)-leak channel, reducing the loading of the ER Ca(2+) store . Regulates intracellular Ca2+ signals, ion channel activity, and cytokine release in the renal tissue . Plays an important role in olfaction, amplifying cAMP-evoked cyclic nucleotide-gated (CNG) channel currents in the olfactory sensory neurons (By similarity). Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity . Can inhibit the activity of ANO1

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TMEM16J protein.

BiowMW :~90.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PIG5; TMEM16J; TP53I5; Anoctamin-9; Transmembrane protein 16J; Tumor protein p53-inducible protein 5; p53-induced gene 5 protein

Immunogen :A synthetic peptide encompassing a sequence within the center region of human TMEM16J.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SLC22A23 expression in Jurkat (A), mouse kidney (B), mouse liver (C), rat brain (D) whole cell lysates.

免疫沉淀（IP）