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CCDC99 polyclonal antibody

货号: BS30961

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30961

Product Name :CCDC99 polyclonal antibody

Swiss-Prot :Q96EA4

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Protein Spindly: Required for the localization of dynein and dynactin to the mitotic kinetochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment . Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) . Plays a role in cell migration

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CCDC99 protein.

BiowMW :~70.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CCDC99; Protein Spindly; hSpindly; Arsenite-related gene 1 protein; Coiled-coil domain-containing protein 99; Rhabdomyosarcoma antigen MU-RMS-40.4A; Spindle apparatus coiled-coil domain-containing protein 1

Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human CCDC99.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Decorin expression in mouse heart (A), mouse liver (B) whole cell lysates.