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NSG1 polyclonal antibody

货号: BS30950

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30950

Product Name :NSG1 polyclonal antibody

Swiss-Prot :P42857

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/200), IF/ICC (1/50 - 1/200)

Background :Neuronal vesicle trafficking-associated protein 1: Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of NSG1 protein.

BiowMW :~20.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :D4S234; Neuron-specific protein family member 1; Brain neuron cytoplasmic protein 1

Immunogen :A synthetic peptide encompassing a sequence within the center region of human NSG1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TET3 expression in HT29 (A), mouse lung (B), rat thymus (C) whole cell lysates.

Immunofluorescent analysis of TET3 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a Alexa Fluor 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.