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GBP5 polyclonal antibody

货号: BS30944

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS30944

Product Name :GBP5 polyclonal antibody

Swiss-Prot :Q96PP8

Host :Rabbit

Reactivity :Human, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Guanylate-binding protein 5: Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (By similarity). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP . Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria (By similarity). Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol (By similarity). Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates t...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of GBP5 protein.

BiowMW :~66.6 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5

Immunogen :A synthetic peptide encompassing a sequence within the center region of human GBP5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Vimentin expression in Molt4 (A), K562 (B), COS7 (C), Jurkat (D), Hela (E) whole cell lysates.

免疫沉淀（IP）