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Adenosine A3 Receptor polyclonal antibody

货号: BS30941

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS30941

Product Name :Adenosine A3 Receptor polyclonal antibody

Swiss-Prot :P0DMS8

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB (1/500 - 1/1000), IF/ICC (1/100 - 1/500)

Background :Adenosine receptor A3: G protein-coupled receptor (GPCR) for adenosine that plays significant roles in various physiological processes including immune regulation, cardioprotection and neuroprotection . Also acts as a receptor for adenosines containing N(6)-methylated adenine (m6A) post-transcriptional modification, which are derived from the degradation of RNAs (mRNAs, rRNAs and tRNAs): activated by N(6)-methyladenosine (m6A), N(6),N(6)-dimethyladenosine (m6,6A) and N(6)-isopentenyladenosine (i6A) . Preferentially couples to the inhibitory G protein (Gi), leading to the suppression of adenylate cyclase activity and a reduction in intracellular cyclic AMP levels . Upon adenosine binding, mediates cardioprotection in cardiomyocytes through anti-apoptotic effects primarily via the ERK1/2 pathway as well as the PI3K pathway . In the central nervous system, participates in the modulation of synaptic plasticity,...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Adenosine A3 Receptor protein.

BiowMW :~36.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Adenosine receptor A3

Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human Adenosine A3 Receptor.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ANKRD28 expression in Hela (A), HT1080 (B), mouse kidney (C), mouse testis (D) whole cell lysates.

免疫沉淀（IP）