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SMIT1 polyclonal antibody

货号: BS30928

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS30928

Product Name :SMIT1 polyclonal antibody

Swiss-Prot :P53794

Host :Rabbit

Reactivity :Human, Rat

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Background :Sodium/myo-inositol cotransporter: Electrogenic Na(+)-coupled sugar symporter that actively transports myo-inositol and its stereoisomer scyllo-inositol across the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1 (By similarity). Maintains myo-inositol concentration gradient that defines cell volume and fluid balance during osmotic stress, in particular in the fetoplacental unit and central nervous system (By similarity). Forms coregulatory complexes with voltage-gated K(+) ion channels, allosterically altering ion selectivity, voltage dependence and gating kinetics of the channel. In turn, K(+) efflux through the channel forms a local electrical gradient that modulates electrogenic Na(+)-coupled myo-inositol influx through the transporter . Associates with KCNQ1-KCNE2 channel in the apical membrane of choroid plexus epithelium and regulates the myo-inositol gradient between blood and cerebrospinal fluid wi...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SMIT1 protein.

BiowMW :~79.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; Sodium/myo-inositol transporter 1; SMIT1; Solute carrier family 5 member 3

Immunogen :A synthetic peptide encompassing a sequence within the center region of human SMIT1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MTGR1 expression in Jurkat (A), HepG2 (B), mouse testis (C), mouse kidney (D), rat brain (E) whole cell lysates.