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JMY polyclonal antibody

货号: BS30920

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30920

Product Name :JMY polyclonal antibody

Swiss-Prot :Q8N9B5

Host :Rabbit

Reactivity :Human, Mouse, Bovine, Chicken, Dog, Porcnine

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Background :Junction-mediating and -regulatory protein: Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions . In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments . Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments . Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. Upon nutrient stress, directly recruited by MAP1LC3B to the...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of JMY protein.

BiowMW :~111 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Junction-mediating and -regulatory protein

Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human JMY.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of GAPDH expression in Hela (A), mouse lung (B), mouse kidney (C), rat kidney (D) whole cell lysates.

免疫沉淀（IP）