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Ataxin 7L3 polyclonal antibody

货号: BS30900

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS30900

Product Name :Ataxin 7L3 polyclonal antibody

Swiss-Prot :Q14CW9

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Ataxin-7-like protein 3: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B . The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex . Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Ataxin 7L3 protein.

BiowMW :~38.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ataxin-7-like protein 3; SAGA-associated factor 11 homolog

Immunogen :A synthetic peptide encompassing a sequence within the center region of human Ataxin 7L3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Karyopherin alpha-6 expression in BT474 (A), SW620 (B), mouse testis (C) whole cell lysates.

免疫沉淀（IP）