Product Name :GPR110 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/200)
Background :Adhesion G protein-coupled receptor (aGPCR) for N-docosahexaenoylethanolamine (synaptamide), an omega-3 fatty acid lipid highly enriched in the brain . Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase . ADGRF1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity . Also able to couple to G(q), G(i) and G(12)/G(13) G proteins; additional evidence is however required to confirm this result in vivo . Involved in the development of neurons and cognitive function (By similarity). In liver, involved in fat accumulation (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of GPR110 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PGR19; Probable G-protein coupled receptor 110; G-protein coupled receptor KPG_012; G-protein coupled receptor PGR19
Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human GPR110.
Modification :Unmodification
