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HORMAD1 polyclonal antibody

货号: BS30861

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30861

Product Name :HORMAD1 polyclonal antibody

Swiss-Prot :Q86X24

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IF/ICC

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/200)

Background :HORMA domain-containing protein 1: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HORMAD1 protein.

BiowMW :~45.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA protein

Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human HORMAD1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IFN beta expression in Hela (A), H1688 (B), H446 (C), mouse lung (D), mouse kidney (E), rat spleen (F) whole cell lysates.

Immunohistochemical analysis of IFN beta staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.