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PIF1 polyclonal antibody

货号: BS30856

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS30856

Product Name :PIF1 polyclonal antibody

Swiss-Prot :Q9H611

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :ATP-dependent DNA helicase PIF1: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PIF1 protein.

BiowMW :~69.8 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C15orf20; ATP-dependent DNA helicase PIF1; DNA repair and recombination helicase PIF1; PIF1/RRM3 DNA helicase-like protein

Immunogen :A synthetic peptide encompassing a sequence within the center region of human PIF1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of LACI expression in U87MG (A) whole cell lysates.

免疫沉淀（IP）