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ABHD8 polyclonal antibody

货号: BS30855

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30855

Product Name :ABHD8 polyclonal antibody

Swiss-Prot :Q96I13

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/100)

Background :Protein ABHD8: Negatively regulates NLRP3-driven inflammation . Promotes NLRP3 degradation through the chaperone-mediated autophagy (CMA) pathway, hence attenuating inflammasome activation and IL1B secretion. Acts by recruiting palmitoyltransferase ZDHHC12 to NLRP3, facilitating NLRP3 palmitoylation and subsequent degradation

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ABHD8 protein.

BiowMW :~47.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Abhydrolase domain-containing protein 8

Immunogen :A synthetic peptide encompassing a sequence within the center region of human ABHD8.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SP1 (Phospho-T453) expression in H1688 (A) whole cell lysates.

Immunohistochemical analysis of SP1 (Phospho-T453) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.