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TESK1 polyclonal antibody

货号: BS30833

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS30833

Product Name :TESK1 polyclonal antibody

Swiss-Prot :Q15569

Host :Rabbit

Reactivity :Human, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Dual specificity testis-specific protein kinase 1: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues (By similarity). Regulates the cellular cytoskeleton by enhancing actin stress fiber formation via phosphorylation of cofilin and by preventing microtubule breakdown via inhibition of TAOK1/MARKK kinase activity (By similarity). Inhibits podocyte motility via regulation of actin cytoskeletal dynamics and phosphorylation of CFL1 (By similarity). Positively regulates integrin-mediated cell spreading, via phosphorylation of cofilin . Suppresses ciliogenesis via multiple pathways; phosphorylation of CFL1, suppression of ciliary vesicle directional trafficking to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 . Probably plays...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TESK1 protein.

BiowMW :~67.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Dual specificity testis-specific protein kinase 1; Testicular protein kinase 1

Immunogen :A synthetic peptide encompassing a sequence within the center region of human TESK1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of p115 expression in BT474 (A), K562 (B), A549 (C) whole cell lysates.

免疫沉淀（IP）