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SSBP1 polyclonal antibody

货号: BS30832

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30832

Product Name :SSBP1 polyclonal antibody

Swiss-Prot :Q04837

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/200), IF/ICC (1/100 - 1/500)

Background :Single-stranded DNA-binding protein, mitochondrial: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) . In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork . Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity . In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK . May also function in mtDNA repair

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SSBP1 protein.

BiowMW :~17.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SSBP; Single-stranded DNA-binding protein mitochondrial; Mt-SSB; MtSSB; PWP1-interacting protein 17

Immunogen :A synthetic peptide encompassing a sequence within the C-term region of human SSBP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PEX1 expression in MCF7 (A) whole cell lysates.

免疫沉淀（IP）