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Complement C6 polyclonal antibody

货号: BS30813

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS30813

Product Name :Complement C6 polyclonal antibody

Swiss-Prot :P13671

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/100)

Background :Complement component C6: Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis . The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways . The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system . Together with component C5b, involved in MAC complex assembly: complement C5b and C6 associate with the outer leaflet of target cell membrane, reducing the energy for membrane bending

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Complement C6 protein.

BiowMW :~105 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Complement component C6

Immunogen :A synthetic peptide encompassing a sequence within the center region of human Complement C6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SCAMP1 expression in HeLa (A), Raw264.7 (B), rat brain (C) whole cell lysates.

免疫沉淀（IP）