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H2AFY polyclonal antibody

货号: BS8670

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8670

Product Name :H2AFY polyclonal antibody

Swiss-Prot :O75367

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :H2AFY polyclonal antibody detects endogenous levels of H2AFY protein.

BiowMW :~ 40kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Core histone macro-H2A.1; Histone macroH2A1; mH2A1; Histone H2A.y; H2A/y; Medulloblastoma antigen MU-MB-50.205; H2AFY; MACROH2A1

Immunogen :Recombinant full length Human H2AFY.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using H2AFY antibody.

Immunofluorescence analysis of U20S cell using H2AFY antibody. Blue: DAPI for nuclear staining.

Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives

JournalJournal Of Cellular And Molecular Medicine

ApplicationIF

IF5.31

SpeciesMouse

PMID33963805
FBXW24 controls female meiotic prophase progression by regulating SYCP3 ubiquitination

JournalClinical and Translational Medicine

ApplicationWB

IF8.554

SpeciesMouse

PMID35858239