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DMGDH polyclonal antibody

货号: BS61706

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61706

Product Name :DMGDH polyclonal antibody

Swiss-Prot :Q9UI17

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :DMGDH (dimethylglycine dehydrogenase), also known as ME2GLYDH or DMGDHD, is an 866 amino acid mitochondrial protein that plays a role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine. Existing as a monomer that belongs to the gcvT family, DMGDH utilizes flavin adenine dinucleotide (FAD) and folate as cofactors. DMGDH is encoded by a gene that maps to human chromosome 5q14.1, defects of which are the cause of DMGDH deficiency (DMGDHD). Patients with DMGDHD experience muscle fatigue, have a fish-like odor and excrete an elevated level of N,N-dimethylglycine (DMG) in urine.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DMGDH polyclonal antibody detects endogenous levels of DMGDH protein.

BiowMW :~ 96 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; DMGDH

Immunogen :Synthetic peptide, corresponding to amino acids 810-860 of Human DMGDH.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DMGDH polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)