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CNTN1 polyclonal antibody

货号: BS61684

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61684

Product Name :CNTN1 polyclonal antibody

Swiss-Prot :Q12860

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumulating evidence implicates cell adhesion molecules in activity-dependent synaptic modifications associated with pairedpulse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecules involved in these processes are the contactins. Contactins are immunoglobulin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regulate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecules, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, and ultimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1,018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1,100 amino acid neural adhesion molecule. The human Contactin 6 gene encodes a 1,028 amino acid neural adhesion molecule.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CNTN1 polyclonal antibody detects endogenous levels of CNTN1 protein.

BiowMW :~ 113 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Contactin-1; Glycoprotein gp135; Neural cell surface protein F3; CNTN1

Immunogen :Synthetic peptide, corresponding Human CNTN1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CNTN1 polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:C6 whole cell lysate(40ug) Lane4:MEF whole cell lysate(40ug)