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GRM1 polyclonal antibody

货号: BS60765

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60765

Product Name :GRM1 polyclonal antibody

Swiss-Prot :Q13255

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-1, which can form a homodimer acts as a receptor for glutamate. It may also be involved in glutamate activity in the CNS.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GRM1 polyclonal antibody detects endogenous levels of GRM1 protein.

BiowMW :~ 132 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Metabotropic glutamate receptor 1; mGluR1; GRM1; GPRC1A; MGLUR1

Immunogen :A synthetic peptide corresponding to residues in Human GRM1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GRM1 polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）