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IFN-γRα (phospho-Y457) polyclonal antibody

货号: BS4697

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS4697

Product Name :IFN-γRα (phospho-Y457) polyclonal antibody

Swiss-Prot :P15260

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-IFN-γRα (Y457) polyclonal antibody detects endogenous levels of IFN-γRα protein only when phosphorylated at Tyr457.

BiowMW :~ 54, 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interferon gamma receptor 1; IFN-gamma receptor 1; IFN-gamma-R1; CDw119; CD119; IFNGR1

Immunogen :Synthetic phosphopeptide derived from human IFN-γRα around the phosphorylation site of Tyrosine 457.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-IFNGR1 (Y457) polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate treated with IFN-γ(100µg/ML,15mins) Lane2:HNIH-3T3 cell lysate treated with IFN-γ(100µg/ML,15mins) Lane3:H9C2 cell lysate treated with IFN-γ(100µg/ML,15mins)