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Ephrin-B1 (phospho-Y317) polyclonal antibody

货号: BS4682

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS4682

Product Name :Ephrin-B1 (phospho-Y317) polyclonal antibody

Swiss-Prot :P98172

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-Ephrin-B1 (Y317) polyclonal antibody detects endogenous levels of Ephrin-B1 protein only when phosphorylated at Tyr317.

BiowMW :~ 38, 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ephrin B1; EphrinB1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2; EFNB1; EFL3; EPLG2; LERK2

Immunogen :Synthetic phosphopeptide derived from human Ephrin-B1 around the phosphorylation site of Tyrosine 317.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-Ephrin-B1 (Y317) polyclonal antibody at 1:500 dilution Lane1:HepG2 cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat skeletal muscle tissue lysate