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APC1 (phospho-S688) polyclonal antibody（KU）

货号: BS4375

价格：￥ 780

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS4375

Product Name :APC1 (phospho-S688) polyclonal antibody（KU）

Swiss-Prot :Q9H1A4

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-APC1 (S688) pAb detects endogenous levels of APC1 protein only when phosphorylated at Ser688.

BiowMW :~ 216 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein; ANAPC1; TSG24

Immunogen :Synthetic phosphopeptide derived from human APC1 around the phosphorylation site of Serine 688

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot (WB) analysis of p-APC1 (S688) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate(40µg) Lane2:K562 whole cell lysate(40µg) Lane3:HEK293T whole cell lysate(40µg)