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CNPase (A108) polyclonal antibody（KU）

货号: BS3461

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3461

Product Name :CNPase (A108) polyclonal antibody（KU）

Swiss-Prot :P09543

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :CNPase (2',3'-Cyclic Nucleotide 3'-Phosphodiesterase) exists in two forms: 46kDa (CNP1) and 48kDa (CNP2). It is expressed at high levels by oligodendrocytes in the central nervous system and by Schwann cells in the peripheral nervous system and is virtual absent in other cell types. CNPase activity is decreased in demyelinating diseases such as multiple sclerosis. CNPase gene is localized to chromosome 17q21, very near the BRCA 1 familial breast cancer gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CNPase (A108) polyclonal antibody detects endogenous levels of CNPase protein.

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,

Alternative Name :2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP

Immunogen :Synthetic peptide, corresponding to amino acids 61-110 of Human CNPase.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CNP pAb at 1:1000 dilution Lane1:The Brain tissue lysate of Mouse(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:CT-26 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:K562 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of CNPase (A108) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Lingo-1 shRNA and Notch signaling inhibitor DAPT promote differentiation of neural stem/progenitor cells into neurons

JournalBrain Research

ApplicationIF,WB

IF2.929

SpeciesRat

PMID26607252